Vehicle-Anti-UAV defence system consists of detection unit, tracking unit, interference unit and background monitoring platform. The detection unit includes a combination of radar, spectrum and audio detection equipment. The radar detection is mainly for the purpose of long-range detection of unmanned aerial vehicles. The spectrum and audio equipment play the role of short-range detection and blindness in the vehicle-mounted Anti-UAV system. Identification, tracking unit mainly contains visible light, infrared optical sensors, interference unit using vehicle interference device. After the detection unit detects the target of invasion, the tracking unit locks the target and calculates the current position information of the target through the monitoring center. At the same time, the interfering device is turned on to adjust the launch angle of the turntable to achieve the effect of driving the invaded target and landing and landing in place.